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 A BRIOTECH BREAKTHROUGH
BRIOTECH, INC. Woodinville, WA 98072, USA briotechusa.com
September 29th, 2016 11:02 AM PDT
PRESS RELEASE
NIH     Scientists     and     collaborators     report     that     Briotech     Inc.’s     proprietary     HOCl formulation    rapidly    inactivates    resistant    infectious    proteins,    known    as    prions,    that cause    Mad    Cow,    Chronic    Wasting,    and    Creutzfeldt–Jakob    Disease,    and    are    now implicated in Alzheimer’s and other chronic brain diseases WOODINVILLE,   Wash.   (September   29,   2016)   Briotech   Inc.   today   announced   that   a study   published   in   the   current   issue   of   PLOS   Pathogens       proves   that   Briotech’s   unique formulation   of   pure   hypochlorous   acid   (HOCl)   inactivates   infectious   proteins,   known as prions, that cause chronic brain diseases in humans and animals.  Investigators   at   the   US   National   Institute   of   Allergy   and   Infectious   Diseases   (NIAID) Rocky   Mountain   Laboratories,   made   the   discovery   in   collaboration   with   researchers   at the    University    of    Washington    (UW)    Bothell,    UW    Seattle,    the    University    of    Verona (Italy),   and   Briotech   Inc.   Their      findings   demonstrate   that   Briotech’s   patent-pending solution   (BrioHOCl TM )   quickly   and   safely   destroys   prions,   the   most   resistant   infectious agents known to medical science. HOCL   is   made   naturally   in   human   white   blood   cells   as   a   key   part   of   the   body’s   internal defense   system.   It   works   as   the   first   line   of   defense   at   wound   sites   to   fight   infection. Briotech’s   proprietary   Electro-Chemical   Activation   (ECA)   technology   enables   large- scale     production     of     this     powerful     natural     compound     for     use     in     consumer     and professional healthcare settings. “We’ve   been   able   to   synthesize   the   same   pure   substance   that   the   body   creates   to defend   itself   as   a   new   weapon   in   the   fight   against   infectious   disease,   and   it’s   a   game changer   for   human   health,”   said   Dan   Terry,   founder,   and   CEO   of   Briotech.   “With   broad adoption   of   BrioHOCl TM ,   we   can   help   stop   the   spread   of   many   infectious   diseases, even   those   caused   by   the   most   highly   resistant   agents   ever   discovered prions and use   the   product   to   save   lives   and   improve   the   health   of   entire   communities   around   the world.    We’re    excited    to    have    this    research    published    in    PLOS    Pathogens ,    and    look forward   to   our   continued   collaboration   with   the   NIH   on   the   effects   of   BrioHOCl TM    on emerging infectious pathogens that threaten global health and safety.” DESTROYING PRIONS Prions    are    abnormal,    misfolded    body    proteins    that    go    out    of    control    and    begin    to multiply   themselves,   spreading   throughout   the   body   and   invading   the   brain.      Prions are   most   commonly   transmitted   orally,   but   can   also   contaminate   medical   and   surgical instruments,   transplanted   tissues,   and   equipment   used   in   food   processing.   A   new,   fast, convenient   and   safe   method   for   decontamination   of   medical   instruments,   surfaces, and     tissues by     simple     immersion     in     an     aqueous     solution     of     Briotech’s     pure BrioHOCl TM can   overcome   a   critically   important   deficiency   in   infection   control   today. It   can   mitigate   risks,   and   limit   liabilities   related   to   healthcare   procedures   and   hospital acquired diseases. Prion   diseases   are   most   widely   known   as   the   cause   of   Mad   Cow   Disease   (BSE).   Prions also   cause   Creutzfeldt-Jakob   Disease   (CJD)   in   humans,   a   fatal   dementia   with   a   long incubation   period.   Recently,   research   has   shown   that   most   other   chronic   degenerative diseases   that   lead   to   dementia,   including   Alzheimer’s,   result   from   prions.   Currently untreatable,      and      inevitably      fatal,      controversy      swirls      around      their      possible transmissibility   as   referenced   in   Nature    ( nature.com/news/the-red-hot-debate-about- transmissible-alzheimers ) Prions    are    uniquely    resistant    to    the    disinfection    and    sterilization    procedures    in common    use    in    healthcare    practice    today.    Extreme    measures    are    needed.    Current prion   decontamination   protocols   are   hazardous   to   people,   damaging   to   instruments and     surfaces,     and     therefore     impractical     for     transmission     control.     “Briotech     has developed   an   enabling   technology,   one   that   offers   for   the   first   time   a   practical   and   safe way   of   destroying   infectious   prions,   the   disease   agents   at   the   very   top   of   the   food chain   when   it   comes   to   resistance   to   disinfection   measures,”   said   Jeff   Williams,   PhD, BVSc,   Chief   Scientific   Officer   at   Briotech.   “We   believe   we’ve   just   exposed   the   tip   of   the iceberg   when   it   comes   to   revealing   the   full   potential   of   the   pure   HOCl   in   controlling and   preventing   many   transmissible   diseases.   That’s   so   important   today   when   rampant antibiotic    resistance    is    challenging    established    approaches    to    infectious    disease management   all   over   the   world.   The   discovery   reported   in   PLOS   Pathogens    has   opened new   avenues   for   researchers   to   explore   in   understanding   the   relationship   between the   HOCl   made   in   the   brain,   its   possible   involvement   in   prion   inactivation   there,   and the   disease   processes   that   lead   to   dementia.   Understanding   those   processes   is   one   of the most urgent priorities facing biomedical science at this time.” HOW IT WORKS BrioHOCl TM     is    easy    to    handle,    safe    for    both    users    and    treated    surfaces    and    is environmentally   safe.   Pure   HOCl,      used   in   the   PLOS   Pathogens    report,   is   reliably   stable in    its    formulation    and    powerfully    effective    against    a    wide    range    of    conventional microbial    disease    agents.    The    solution    can    be    applied    directly    to    skin    and    mucous membranes,   hard   surfaces,   instruments,   or   safely   aerosolized   to   decontaminate   entire rooms. Briotech    manufactures    BrioHOCl TM     in    fully-automated    production    platforms    inside 20’   shipping   containers,   enabling   production   and   distribution   of   a   consistent   and   pure form of HOCl virtually anywhere in the world. ABOUT BRIOTECH INCORPORATED Based   in   Woodinville,   WA,   the   company   was   founded   in   2013   to   commercialize   the production   of   pure   HOCl,   a   powerful,   safe,   naturally   occurring   substance,   effective against   the   whole   range   of   infectious   disease   pathogens   of   humans   and   animals,   and   to make      it      readily      available      throughout      the      world.      Briotech’s      introduction      of transportable,   self-contained   manufacturing   systems   makes   high   volume   production of     consistent     and     reliable     HOCl     solutions     possible     for     the     first     time     ever.     Its proprietary   electrolysis   technology   creates   unique   formulations   of   stable   HOCl   for   a wide   range   of   applications   in   consumer,   medical,   agricultural   and   industrial   settings. More information is available at briotechusa.com . ABOUT THE RESEARCH STUDY The      research      study      titled      “Inactivation      of      Prions      and      Amyloid      seeds      with Hypochlorous Acid” appears in the current issue of PLOS Pathogens  here: los.org/10.1371/journal.ppat.1005914 BrioHOCl TM       treatment   led   to      a   high   level   of   inactivation   after   short   exposure   times for   transmissible   prions   of   CJD,   BSE,   and   CWD,   but   also   for   self-replicating   proteins found    in    Alzheimer’s,    Parkinson’s    and    other    dementias.    Infectivity    of    BrioHOCl TM   treated scrapie prions in mice was also highly significantly reduced.
BRIOTECH, ITS LOGOS, LANGUAGE, AND IMAGES ARE TRADEMARKS AND/OR THE COPYRIGHT PROPERTY OF BRIOTECH, INC. AND/OR ITS AFFILIATES. © 2013-2017
BRIOTECH, ITS LOGOS, LANGUAGE, AND IMAGES ARE TRADEMARKS AND/OR THE COPYRIGHT PROPERTY OF BRIOTECH, INC. AND/OR ITS AFFILIATES. © 2013-2017
A BRIOTECH BREAKTHROUGH
READ MORE
BRIOTECH, INC. Woodinville, WA 98072, USA briotechusa.com
September 29th, 2016 11:02 AM PDT
NIH   Scientists   and   collaborators   report   that   Briotech   Inc.’s proprietary    HOCl    formulation    rapidly    inactivates    resistant infectious   proteins,   known   as   prions,   that   cause   Mad   Cow, Chronic    Wasting,    and    Creutzfeldt–Jakob    Disease,    and    are now     implicated     in     Alzheimer’s     and     other     chronic     brain diseases WOODINVILLE,   Wash.   (September   29,   2016)   Briotech   Inc. today   announced   that   a   study   published   in   the   current   issue of   PLOS   Pathogens       proves   that   Briotech’s   unique   formulation of     pure     hypochlorous     acid     (HOCl)     inactivates     infectious proteins,   known   as   prions,   that   cause   chronic   brain   diseases in humans and animals.  Investigators    at    the    US    National    Institute    of    Allergy    and Infectious    Diseases    (NIAID)    Rocky    Mountain    Laboratories, made   the   discovery   in   collaboration   with   researchers   at   the University      of      Washington      (UW)      Bothell,      UW      Seattle,            the    University    of    Verona    (Italy),    and    Briotech    Inc.    Their findings       demonstrate       that       Briotech’s       patent-pending solution   (BrioHOCl TM )   quickly   and   safely   destroys   prions,   the most resistant infectious agents known to medical science. HOCL    is    made    naturally    in    human    white    blood    cells    as    a                key   part   of   the   body’s   internal   defense   system.   It   works   as the    first    line    of    defense    at    wound    sites    to    fight    infection. Briotech’s    proprietary    Electro-Chemical    Activation    (ECA) technology   enables   large-scale   production   of   this   powerful natural    compound    for    use    in    consumer    and    professional healthcare settings. “We’ve    been    able    to    synthesize    the    same    pure    substance          that   the   body   creates   to   defend   itself   as   a   new   weapon   in   the fight   against   infectious   disease,   and   it’s   a   game   changer   for human   health,”   said   Dan   Terry,   founder,   and   CEO   of   Briotech. “With   broad   adoption   of   BrioHOCl TM ,   we   can   help   stop   the spread   of   many   infectious   diseases,   even   those   caused   by   the most    highly    resistant    agents    ever    discovered prions and use   the   product   to   save   lives   and   improve   the   health   of   entire communities    around    the    world.    We’re    excited    to    have    this research   published   in   PLOS   Pathogens ,   and   look   forward   to our   continued   collaboration   with   the   NIH   on   the   effects   of BrioHOCl TM    on   emerging   infectious   pathogens   that   threaten global health and safety.” DESTROYING PRIONS Prions    are    abnormal,    misfolded    body    proteins    that    go    out                of     control     and     begin     to     multiply     themselves,     spreading throughout   the   body   and   invading   the   brain.      Prions   are   most commonly     transmitted     orally,     but     can     also     contaminate medical   and   surgical   instruments,   transplanted   tissues,   and equipment   used   in   food   processing.         A   new,   fast,   convenient and       safe       method       for       decontamination       of       medical instruments,   surfaces,   and   tissues by   simple   immersion   in an    aqueous    solution    of    Briotech’s    pure    BrioHOCl TM can overcome     a     critically     important     deficiency     in     infection control   today.   It   can   mitigate   risks,   and   limit   liabilities   related to healthcare procedures and hospital acquired diseases. Prion   diseases   are   most   widely   known   as   the   cause   of   Mad Cow    Disease    (BSE).    Prions    also    cause    Creutzfeldt-Jakob Disease    (CJD)    in    humans,    a    fatal    dementia    with    a    long incubation   period.   Recently,   research   has   shown   that   most other   chronic   degenerative   diseases   that   lead   to   dementia, including       Alzheimer’s,       result       from       prions.       Currently untreatable,   and   inevitably   fatal,   controversy   swirls   around their     possible     transmissibility     as     referenced     in     Nature   / / r - alzheimers ) Prions     are     uniquely     resistant     to     the     disinfection     and sterilization     procedures     in     common     use     in     healthcare practice   today.   Extreme   measures   are   needed.   Current   prion decontamination      protocols      are      hazardous      to      people, damaging     to     instruments     and     surfaces,     and     therefore impractical   for   transmission   control.   “Briotech   has   developed an   enabling   technology,   one   that   offers   for   the   first   time   a practical    and    safe    way    of    destroying    infectious    prions,    the disease    agents    at    the    very    top    of    the    food    chain    when    it comes     to     resistance     to     disinfection     measures,”     said     Jeff Williams,    PhD,    BVSc,    Chief    Scientific    Officer    at    Briotech.      “We   believe   we’ve   just   exposed   the   tip   of   the   iceberg   when        it   comes   to   revealing   the   full   potential   of   the   pure   HOCl   in controlling     and     preventing     many     transmissible     diseases. That’s      so      important      today      when      rampant      antibiotic resistance       is       challenging       established       approaches       to infectious     disease     management     all     over     the     world.     The discovery     reported     in     PLOS     Pathogens      has     opened     new avenues    for    researchers    to    explore    in    understanding    the relationship     between     the     HOCl     made     in     the     brain,     its possible    involvement    in    prion    inactivation    there,    and    the disease    processes    that    lead    to    dementia.    Understanding those   processes   is   one   of   the   most   urgent   priorities   facing biomedical science at this time.” HOW IT WORKS BrioHOCl TM    is   easy   to   handle,   safe   for   both   users   and   treated surfaces   and   is   environmentally   safe.   Pure   HOCl,      used   in   the PLOS    Pathogens     report,    is    reliably    stable    in    its    formulation and   powerfully   effective   against   a   wide   range   of   conventional microbial   disease   agents.   The   solution   can   be   applied   directly to   skin   and   mucous   membranes,   hard   surfaces,   instruments, or safely aerosolized to decontaminate entire rooms. Briotech      manufactures      BrioHOCl TM       in      fully-automated production   platforms   inside   20’   shipping   containers,   enabling production    and    distribution    of    a    consistent    and    pure    form              of HOCl virtually anywhere in the world. ABOUT BRIOTECH INCORPORATED Based    in    Woodinville,    WA,    the    company    was    founded    in 2013    to    commercialize    the    production    of    pure    HOCl,    a powerful,     safe,     naturally     occurring     substance,     effective against   the   whole   range   of   infectious   disease   pathogens   of humans     and     animals,     and     to     make     it     readily     available throughout        the        world.        Briotech’s        introduction        of transportable,   self-contained   manufacturing   systems   makes high    volume    production    of    consistent    and    reliable    HOCl solutions    possible    for    the    first    time    ever.    Its    proprietary electrolysis   technology   creates   unique   formulations   of   stable HOCl   for   a   wide   range   of   applications   in   consumer,   medical, agricultural     and     industrial     settings.     More     information     is available at briotechusa.com . ABOUT THE RESEARCH STUDY The   research   study   titled   “Inactivation   of   Prions   and   Amyloid seeds   with   Hypochlorous   Acid”   appears   in   the   current   issue of PLOS Pathogens  here: los.org/10.1371/journal.ppat.1005914 BrioHOCl TM treatment    led    to        a    high    level    of    inactivation after   short   exposure   times   for   transmissible   prions   of   CJD, BSE,   and   CWD,   but   also   for   self-replicating   proteins   found   in Alzheimer’s,   Parkinson’s   and   other   dementias.   Infectivity   of BrioHOCl TM treated   scrapie   prions   in   mice   was   also   highly significantly reduced.
PRESS RELEASE
BRIOTECH, ITS LOGOS, LANGUAGE, AND IMAGES ARE TRADEMARKS AND/OR THE COPYRIGHT PROPERTY OF BRIOTECH, INC. AND/OR ITS AFFILIATES. © 2013-2017
BRIOTECH, ITS LOGOS, LANGUAGE & IMAGES ARE TRADEMARKS & THE COPYRIGHT PROPERTY OF BRIOTECH, INC. & ITS AFFILIATES. © 2013-2017